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JIVA Fertility

Frozen Embryo Treatment (FET)

Advances in embryo freezing (cryopreservation) technology have made frozen embryo treatment (FET) a fertility treatment option which will give you another opportunity to achieve pregnancy without having to undergo stimulation of ovaries or the egg collection procedure. We can freeze good-quality embryos during an IVF/ICSI treatment cycle which can later be thawed and transferred inside the womb cavity, after suitable preparation of the endometrium (lining of the womb).

We can arrange a FET cycle at any time after your initial treatment, once you feel physically and psychologically ready to have further treatment. If you have had a successful pregnancy, we advise you to stop breast feeding before FET.

Natural cycle or hormone-regulated (medicated) cycle?

If you have regular menstrual periods, FET can be done in your natural menstrual cycle without using any hormones. Hormone regulated (medicated FET) cycle will be required if you have irregular menstrual cycle. Both treatments are equally effective, but there are pros and cons to each.

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A majority of the FET we offer through JIVA Fertility are medicated FET as the natural cycle FET is dependent on your ovulation which may happen on a day when we are unable to arrange the embryo transfer and hence the treatment cycle will have to be cancelled. If you wish to have a natural cycle FET, it is important that you are aware of this possibility. Having a medicated FET avoids this risk. Cancelling a treatment cycle will be disappointing for all of us, however it will not affect the embryos in any way, as they would not have been thawed out.

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In medicated FET, we ‘switch-off’ your ovaries using hormone injections, and use oestrogen (tablets and/or patches) and progesterone (pessaries and/or injections) hormones to prepare the lining of your womb which are continued until 12 weeks of pregnancy. As we control the treatment cycle, we can arrange embryo transfer when convenient to you and us.

What do you need to do?

Once you have been seen by one of our consultants to discuss FET, you will be advised to contact our team on the first day of your menstrual periods and one of us will confirm to you within a few days when we are able to arrange the treatment for you and to plan your treatment cycle. Occasionally, we may have to ask you to contact us in the following cycle. We advise you not to have unprotected intercourse from the first day of your period until after the embryo transfer.

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We will explain the treatment in detail and teach you how to self-administer injections to suppress your natural hormones which will be continued until you are ready for embryo transfer. We will also arrange for the medications to be delivered to your home address and we will get you and where applicable your partner, to sign a patient agreement prior to any embryos being thawed.

Suppressing your natural hormones

We use either daily injections (Buserelin) or one injection that works for four weeks (Prostap). Around two weeks later, you will be given an appointment to attend for a trans-vaginal ultrasound scan.

Stimulation of the endometrium (lining of the womb)

If we are satisfied othe ultrasound scan that the initial injection has worked, we will give you specific instructions on when to start Oestrogen tablets/patches to stimulate the lining of the womb. We will provide an appointment 12 days later for another trans-vaginal scan to check if Oestrogen has thickened the lining of the womb sufficiently. If the lining is not thick enough, we will continue Oestrogen for another 5-7 days before a further ultrasound scan can be undertaken.

Luteal Phase support

If the thickness of the womb lining appears appropriate on the ultrasound scan, we will give you specific instructions about when to start progesterone pessaries (and/or injections) to help to support the lining of the womb, while continuing Oestrogen. We will confirm the date for the embryo transfer procedure.

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The pessaries can be inserted either inside the vagina or through the back passage. On the morning of the day of your embryo transfer, please insert the pessary in your back passage rather than the vagina.

Embryo Transfer

On the morning of the embryo transfer, an embryologist will telephone you to let you know whether the embryo has survived the thaw process and advise you of the date/time to attend the unit for embryo transfer procedure. We know that 80-85% of the embryos survive the process of freezing and thawing. You will be asked to attend with a full bladder, as an abdominal ultrasound scan will be carried out to ensure that the embryo is placed in the correct part of the womb cavity. The embryo transfer procedure takes around 10-15 minutes, and no anaesthetic is necessary. Your partner will be able to come with you into the embryo transfer procedure room. You will be able to go home straight after the procedure.

Outcome

We advise you to continue Oestrogen and Progesterone until your pregnancy test date which would have been given to you. You should use the first urine sample in the morning and a good quality urine pregnancy test kit.

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Please contact us to advise the outcome of the urine pregnancy test so that we can arrange an early pregnancy scan for you if it is positive or a Review appointment if negative. You will continue Oestrogen and Progesterone until 12 weeks of pregnancy if the pregnancy scan is normal.

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We will advise you to stop Oestrogen and Progesterone if the pregnancy test is negative.

Cost of FET

The cost of FET depends on the clinic and type of medications used. For detailed pricing, please refer to our Cost of Treatments page.

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If you have embryos stored in one of our partner clinics and wish to have personalised advice to proceed with FET, please schedule a consultation with our fertility specialists at JIVA Fertility.

Success rates of FET

Success rates for FET have steadily increased over the years. The success rates of FET are similar to fresh embryo transfer.

Factors influencing the success rates of FET

Female partner's Age at embryo creation

Embryo Quality

Endometrial Preparation

Cryopreservation Technique

Previous pregnancies

BMI and lifestyle

Clinician's Expertise

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At JIVA Fertility, we are committed to providing expert medical care, emotional support, and tailored treatment plans to help you achieve successful pregnancy.

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New York, NY 10001

123 Main Street

Apt 4B

Contact: +123 456-7890

Los Angeles, CA 90012

456 Elm Avenue

Suite 300

Contact: +122 555-1212

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